Streptococcus Group A (Deadly Diseases and Epidemics) - ISBN:0791083462

Streptococcus Group A (Deadly Diseases and Epidemics)

Date: 22 April 2011, 12:34

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The group A beta-hemolytic streptococcus (GABHS; species name, Streptococcus pyogenes) is a species of bacteria that can cause a wide variety of diseases. Some of these diseases may be superficial (nonlethal) diseases, such as pharyngitis (“strep throat”) and impetigo (a skin disease). However, infections caused by some strains (isolates that are identical at the genetic level) of this type of bacterium can also cause diseases with a high fatality rate, such as necrotizing fasciitis (NF) and streptococcal toxic shock syndrome (STSS). In addition, diseases caused by these bacteria do not necessarily stop affecting the person when the infection is eliminated. Indeed, some diseases only begin to manifest symptoms days or weeks after the bacteria have been cleared from the body. These delayed diseases, called postinfection sequelae, are most often due to an aberrant immune response by the host. Some postinfection sequelae include glomerulonephritis (a disease of the kidneys), rheumatic fever, and rheumatic heart disease. The group A streptococcus is also able to cause scarlet fever, which is a rash caused by toxins produced by the bacteria during a throat infection; and puerperal fever, which is an infection of the blood that was, at one time, a leading cause of mortality among women who had recently given birth.

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