Stereoselective Synthesis, 2nd edition - ISBN:3521292438

Stereoselective Synthesis, 2nd edition

Date: 13 April 2011, 14:53

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The quest for selectivity in synthesis still continues as the most important focal area for chemists, and the drive for stereoselectivity is among the most coveted goals. For the past fifty years, organic chemists have pursued the understanding and control of stereochemical behavior, and in 1956 an outstanding monograph appeared entitled “Steric Effects in Organic Chemistry”, edited by M. S. Newman. This work placed stereochemistry, both qualitatively and quantitatively, in its proper position of importance in organic chemistry. Following this, in 1969, Hassel and Barton shared a Nobel Prize for the concepts of molecular conformation, further propelling stereochemistry into the limelight. Again, in 1975, the Nobel Prize was awarded to Cornforth and Prelog for stereochemical reactions, and further intensified efforts to enhance both relative and absolute stereoselectivity.

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