Protein Condensation: Kinetic Pathways to Crystallization and Disease - ISBN:0521851211

Protein Condensation: Kinetic Pathways to Crystallization and Disease

Date: 14 April 2011, 00:07

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This book deals with a truly interdisciplinary subject: protein condensation from solution. We use “condensation” in this book to denote one of several forms of proteins: a dense, protein-rich fluid phase, an amorphous aggregate, a gel, a crystal, or a polymer fiber. All these forms have been observed experimentally and are important in their own right. The primary purpose of the book is to bring to a wide audience the current status of research in the field, which is still evolving at a rapid rate. The bulk of the book deals with issues related to producing high quality protein crystals from solution, in which the bottleneck is crystal nucleation. Here the main challenge is to determine the initial solution conditions so that optimal crystal nucleation occurs.

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