The Comet Assay in Toxicology - ISBN:0854041990

The Comet Assay in Toxicology

Date: 14 April 2011, 11:08

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This book is the first of its kind to be devoted exclusively to the Comet assay and its applications as an important tool in current toxicology. This multiauthor book will serve as both a reference and a guide for investigators in the biomedical, biochemical and pharmaceutical sciences. Specialists from the fields of genetic toxicology and human epidemiology, with first-hand knowledge of their chosen subspecialities, have contributed to this peer-reviewed scientific venture. Simplicity, rapidity, versatility and ease of application of the Comet assay have made it a favourite amongst researchers and it is now also gaining acceptance amongst regulators. It can be used in all single cells from prokaryotes and eukaryotes, in plants and animals including humans, involving both somatic and germ cells. It is also a relatively inexpensive assay to perform. The book is divided into different sections, reflecting the range of interest in the exploitation of this assay. It begins with an introductory section reviewing the genesis of the assay for those new to the technique, and details the various fields in which it finds wide acceptance. This sets the scene by explaining why the assay has become the most sensitive and sought after assay in modern toxicology.

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