Surfaces and Interfaces for Biomaterials - ISBN:1855739305

Surfaces and Interfaces for Biomaterials

Date: 27 April 2011, 07:54

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Biomaterials research has under gone a variety of evolutionary, one might say revolutionary, developments in recent years. The full entry of biomaterials as a credible modality in modern medicine was essentially triggered by the work of John Charnley on hip replacement. Then, as now, bulk materials properties and biomechanics took centre stage in view of the stringent mechanical and tribological demands of the implants. However, such issues cannot be the sole determinants of clinical outcome . Interest in bulk properties has inevitably shifted to the important consideration of the surface with the plethora of allied interfacial phenomena , conditioning clinical outcome. A consideration of the interface goes beyond the realms of an intellectual research exercise given that, even today, implants are better characterise d by a bioincompatibility, rather than the hoped for ‘inertness’ of biocompatibility.

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