Periodic Presumptive Treatment for Sexually Transmitted Infections
Date: 15 April 2011, 17:53
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This publication summarizes the deliberations of the technical consultation, which covered current knowledge on periodic presumptive treatment and experiences to date with interventions, including the conditions that seem to be the most favourable for such interventions to work well. Further research is clearly needed in this field – including research employing possible modelling with current field data. Recommendations for research, as well as guidelines for those carrying out programmes with periodic presumptive treatment, were formulated and are presented in the final section of this publication. Contents: Abbreviations i Acknowledgements ii Executive summary iii 1. Introduction 1 2. Objectives 2 3. Participants and methodology 2 4. What is periodic presumptive treatment? 3 4.1 Definitions 3 4.2 A continuum of approaches 3 5. Sex worker populations 4 6. Experiences of one-time presumptive treatment for STIs among core groups 4 Angeles City, Philippines 4 Antananarivo and Tamamave, Madagascar 4 Sihanoukville, Cambodia 5 7. Experiences of periodic presumptive treatment for STIs among core groups 6 7.1 Periodic presumptive treatment within the context of existing STI services 6 South African mining communities 6 Conclusions 7 Hillbrow sex worker intervention, Johannesburg, South Africa 7 Conclusions 8 Nairobi, Kenya 8 Conclusions 8 Cotonou and Porto-Novo, Benin and Accra, Ghana 9 Conclusions 10 Mysore, India 10 Conclusions 11 7.2 Periodic presumptive treatment outside of routine STI services 11 The Lao People’s Democratic Republic 11 Conclusion 12 8. Conclusions, recommendations and priorities for further research 13 8.1 Uses of presumptive treatment and periodic presumptive treatment for STI control 13 One-time presumptive treatment 13 Periodic presumptive treatment 13 8.2 Approaches to operating periodic presumptive treatment 13 8.3 Evaluation of the effectiveness of periodic presumptive treatment 14 Effectiveness 14 Cost-effectiveness 14 Mobility 15 8.4 The impact of periodic presumptive treatment on specific STIs 15 Coverage of specific STIs 15 Chancroid 15 Trichomoniasis 15 Genital herpes 15 HIV transmission 15 8.5 Operating periodic presumptive treatment programmes 16 Periodicity, tapering and the duration of programmes 16 Inclusiveness 16 Training 16 8.6 Drug resistance 16 8.7 Uses of modelling 17 Annex 1. References 18 Annex 2. List of participants 19
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