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Parasites And Allergy
Parasites And Allergy
Date: 14 April 2011, 10:41

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One of the key words of immunology at the beginning of the 21st century is ‘regulation’. Twenty-five years later the Th1/Th2 paradigm, the concept of regulatory cell populations, is now in the heart of our understanding of immune response. Helminths and allergic conditions are recognized as the main Th2 cell inducers. The negative association of allergic manifestations and helminth infections has been debated for over 30 years. It is, however, only in the recent past, that modulation of allergy by helminth infections has been clearly substantiated and shown to be consistent with the activity of regulatory cell populations, which control effector mechanisms of both Th1 and Th2 types.

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