Natural Product Chemistry for Drug Discovery - ISBN:0854041931

Natural Product Chemistry for Drug Discovery

Date: 28 April 2011, 04:45

Free register and download UseNet downloader, then you can FREE Download from UseNet.

Download without Limit " Natural Product Chemistry for Drug Discovery " from UseNet for FREE!

Natural products hold a special place in drug discovery having provided and
inspired numerous life saving medicines and medical breakthroughs, particularly
in the treatment of infectious diseases, cancer, hypercholesterolemia and
immunological disorders. Twenty one drugs approved for marketing between
2003 and 2008 owe their existence to natural product leads discovered from
mainly actinomycete, bacteria and fungal sources.1 It has been our intention
with this book to not only provide insights into the likely sources and methodologies
that may be used to discover new natural product based drugs in
the future, but also to stress the utility and importance of this approach to
drug discovery in terms of new clinical candidates and recent commercial
successes.
The final section of this book provides fascinating accounts of the twists,
turns and pitfalls, as well as the role serendipity played, in the successful
development and commercialisation of daptomycin and micafungin. Accounts
of natural product derived drug candidates which are currently being evaluated
in clinical trials may be found in Chapters 11–13, with salinosporamide A and
bevirimat described in detail. The pipeline of 36 drug candidates which are in
late stage clinical development may imply a continuing role for natural products
in drug discovery, but we will return to this issue towards the end of this
preface. Before then, let us look at the earlier chapters which follow in this

Download Links:

Download Link (High Speed Download)

Download Link (http://rapidshare.com/...Na)

DISCLAIMER:

This site does not store Natural Product Chemistry for Drug Discovery on its server. We only index and link to Natural Product Chemistry for Drug Discovery provided by other sites. Please contact the content providers to delete Natural Product Chemistry for Drug Discovery if any and email us, we'll remove relevant links or contents immediately.