Molecular Biology of Drug Addiction - ISBN:1588290603

Molecular Biology of Drug Addiction

Date: 14 April 2011, 18:05

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The neurobiological mechanisms involved in drug addiction have been investigated for several decades with a variety of pharmacological and biochemical approaches. These studies have associated several neuroanatomical and neurochemical mechanisms with different components of drug-addictive processes, and this has led to the identification of possible targets for new treatment strategies. Progress has been accelerated dramatically in the last few years by novel research tools that selectively remove or enhance the expression of specific genes encoding proteins responsible for the biological responses of these drugs. These new models, most of them obtained from the recent advances in molecular biology’s technology, have provided definitive advances in our understanding of the neurobiological mechanisms of drug addiction. Classical behavioral, biochemical, and anatomical techniques have been adapted to take a maximum advantage of these new molecular tools.

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