Metal Ions in Biological Systems: Metal Ions and Their Complexes in Medication, Volume 41 - ISBN:B000PMGIV8

Metal Ions in Biological Systems: Metal Ions and Their Complexes in Medication, Volume 41

Date: 30 April 2011, 04:54

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ASIN: B000PMGIV8
The early development of quantified risk analysis took place largely in the aerospace and
nuclear industries. In these industries there is a readily definable ‘top event’ (airplane
crash, reactor meltdown) whose consequences are regarded as being wholly unacceptable. For this reason the safety case tends to be based heavily on probabilistic arguments; that is to say it must be demonstrated that the ‘top event’ has only a certain (low) probability of occurring. The safety case does not tend to rely on demonstrating that the consequences of the top event are in some way tolerable. The situation in the process industries is different with the application of quantified risk assessment having a greater emphasis on the examination of incident consequences. That this is so is related to the fact that it is not economic, nor is it necessary from a safety viewpoint, to construct process plant such that leakage of hazardous product has a ‘negligible’ probability. For an offshore installation it is necessary to demonstrate that process leakage cannot by itself or via an escalation of the incident lead to significant loss of life or platform loss. For small onshore chemical plants it may simply be necessary to show that such leakage cannot generate a hazard to the surrounding population...

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