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Metabolic Engineering: Principles and Methodologies
Metabolic Engineering: Principles and Methodologies
Date: 13 April 2011, 02:41

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Metabolic engineering is about the analysis and modification of metabolic pathways. The field emerged during the past decade, and powered by techniques from applied molecular biology and reaction engineering, it is becoming a focal point of research activity in biological and biochemical engineering, cell physiology, and applied microbiology. Although the notion of pathway manipulation had been discussed before, the vision of metabolic engineering as defining a discipline in its own right was first suggested by Bailey in 1991. It was embraced soon thereafter by both engineers and life scientists who saw in it the opportunity to capture the potential of sequence and other information generated from genomics research.

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