Malassezia and the Skin: Science and Clincial Practice - ISBN:3642036155

Malassezia and the Skin: Science and Clincial Practice

Date: 14 April 2011, 12:24

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It has been known for many years that the Malassezia yeasts are associated with a number of different human diseases ranging from pityriasis versicolor to seborrhoeic dermatitis. However the evolving history of their taxonomy and pathogenicity, and the management of the diseases that they cause has been a long, and often difficult, journey. Their fastidious growth requirements defied the initial attempts to culture these organisms on laboratory media and their true identification and the relationship between different species only became apparent with the application of modern molecular techniques. Likewise although recognised in the 19th century as potential causes of human infection, piecing together the complex and, in certain cases, still uncertain relationships to different human diseases has taken many years. Recognised initially as causes of infection of the skin, they are now known to be superficial commensals as well as potential causes of infections in domestic animals and more serious human conditions such as fungemia. They have also been implicated in the pathogenesis of allergic and other inflammatory diseases.

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