Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management (Current Clinical Neurology) - ISBN:1588294242

Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management (Current Clinical Neurology)

Date: 14 April 2011, 10:41

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The last decade witnessed vast scientific advances in our understanding of molecular mechanisms of the inflammatory cascade involved in pathogenesis of diverse neurological disorders. Endothelial cells, activated leukocytes, resident immune cells within the central nervous system (CNS), and many classes of inflammatory mediators, especially chemokines and cytokines, are the major components of this complex and largely unsolved pathological puzzle. Through innumerable experiments, we have learned more about the role of each one of these players in the course of the inflammatory response, and have become able to apply some of our knowledge toward the development of more effective treatments with fewer adverse effects.

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