In Pursuit of the Gene: From Darwin to DNA - ISBN:0674026705

In Pursuit of the Gene: From Darwin to DNA

Date: 27 April 2011, 10:04

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From Publishers Weekly
Starred Review. Understanding the nature of genetic inheritance was essential for evolution to be accepted as the dominant paradigm in biology. In a masterful work, science writer Schwartz looks at the science and the personalities behind that understanding, ranging from Darwin's belief in pangenesis to explain the inheritance of physical variations to Hermann Muller's Nobel Prize–winning work on X-rays and genetic mutation. Although he discusses the contributions of such luminaries as Francis Galton, William Bateson, Gregor Mendel, Hugo de Vries and Thomas Hunt Morgan, Schwartz provides far more than character sketches. In a thoroughly accessible manner, he offers insight into the critical experiments each undertook and allows readers to share the excitement of discovery. He also does a fabulous job of demonstrating the social nature of science, showing how competition often leads to unseemly actions and how the unwillingness to part with a favorite theory leads to an idiosyncratic interpretation of data. Schwartz illustrates how, despite all of this, science continues to make progress and our understanding of the world continues to grow. Although the history of genetics has been covered many times before, Schwartz brings unbridled energy, strong writing and a fresh perspective. 42 b&w illus. (Apr.)
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From Booklist
Schwartz’s scientific history of the origin of genetics spans from 1868, when Darwin proposed an incorrect theory of heredity, to 1944, when DNA was proven to be the molecule of heredity. Schwartz uses an accessible biographical structure, in which the main players conduct experiments, carry on arguments, and eventually put genetics on the right course. Schwartz’s emphasis on those who sent it up blind alleys underscores the difficulty of the heredity problem. Schwartz begins his profile of Darwin when he was a grand old man receiving visitors. One, Francis Galton, went off on a eugenics tangent but bequeathed a statistical approach that proved fruitful, while another, botanist Hugo de Vries, conceived the idea of mutations. The rediscovery in the early 1900s of Gregor Mendel’s work, which, as Schwartz explains, was resisted by scientists influenced by Darwin’s wrong ideas about inheritance, led to the celebrated work of Thomas Hunt Morgan and Hermann Muller, who pioneered gene mapping and manipulation. Thorough and detailed, Schwartz’s history is a solid source for learning about the pioneers of genetics. --Gilbert Taylor

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