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Domino Reactions in Organic Synthesis
Domino Reactions in Organic Synthesis
Date: 13 April 2011, 17:12

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The ability to create complex molecules in only a few steps has long been the dream of chemists. That such thinking is not unrealistic could be seen from Nature, where complicated molecules such as palytoxin, maitotoxin and others are synthesized with apparent ease and in a highly efficient manner. Now, with the development of domino reactions, the dream has become almost true for the laboratory chemist ? at least partly. Today, this new way of thinking represents a clear change of paradigm in organic synthesis, with domino reactions being frequently used not only in basic research but also in applied chemistry. The use of domino reactions has two main advantages. The first advantage applies to the chemical industry, as the costs not only for waste management but also for energy supplies and materials are reduced. The second advantage is the beneficial effect on the environment, as domino reactions help to save natural resources. It is, therefore, not surprising that this new concept has been adopted very rapidly by the scientific community.

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