Concepts in Bacterial Virulence - ISBN:3805577869

Concepts in Bacterial Virulence

Date: 14 April 2011, 13:48

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With the current volume of the Karger bouk series Contribulions to Microbiology, we attempt to summarize some of the most imponant virulence mechanisms in bacterial infectious diseases. In many cases the disease pathway begins with the invasion of the host and ends with the outbreak of physiological responses that may lead 10 severe complications and ultimately death. Over the years it has been shown that the interplay between pathogenic bacteria and the host is complex and finely balanced. The ability of successful pathogens to survive in an immunologically hostile environment is provided by a large armamentarium of virulence mechanisms, which includes bacterial factors thai evade, neutralize or counter the host defense systems, but also manipulate host homeostasis and nonnal cell functions. In order to give a comprehensive update, we were able to recmit some ofthe most eminent scientists in infectious diseases to give an overview of the most important recent findings in their fields. We hope that this volume provides a thought-provoking update on these important medical issues.

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