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Actin-Monomer-Binding Proteins
Actin-Monomer-Binding Proteins
Date: 13 April 2011, 15:33

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Since its discovery more than 60 years ago by F.B. Straub, it has become evident that actin plays a fundamental role in a vast number of cellular processes. The regulated polymerization of actin filaments provides force for cell migration, endocytosis, phagocytosis, and a number of morphogenetic processes such as formation of axons and dendrites in neurons. Consequently, the actin cytoskeleton is also intimately involved in a variety of developmental processes in multicellular organisms. Actin is conserved among all eukaryotic organisms and recent studies have also identified actin homologues from prokaryotes. This indicates the importance of actin in the evolution of life.

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